News

Researchers at Cardiff University created the first stem cell platform based on Alzheimer’s polygenic risk scores. Using cells from 100 individuals, the resource enables study of genetic risk factors in brain cells.

A Swedish twin study shows that genetics explain up to 70% of infant crying duration by 5 months of age. While sleep disruptions and settling time are more influenced by environment early on, genetics play a growing role over time.

Researchers found that a single silent mutation in a cucumber gene changes RNA structure, leading to 70% longer fruits. This discovery reveals that non-coding regions can shape plant traits.

Researchers at the University of California Davis Comprehensive Cancer Center have uncovered an evolutionary change that may explain why human immune cells are less effective at combating solid tumors compared to our closest living ancestors.

Researchers sequenced the genome of a sea spider, revealing it lacks whole-genome duplication seen in related arachnids. This positions sea spiders near the base of the chelicerate family tree. The study also found they’re missing a key Hox gene.

A study used single-cell transcriptomics to analyze maternal–fetal interfaces in six mammalian species. The team discovered ancient, conserved gene signatures linked to placental development.

A new tool, Variant-aware Cas-OFFinder, enhances CRISPR-Cas9 predictions by factoring in genetic variations like SNPs and deletions. It provides more accurate, personalized genome editing strategies for humans and plants.

Researchers have uncovered compelling genomic evidence that points to air pollution and other environmental exposures as a potential major factor behind the development of lung cancer in never-smokers.

An oral drug called MA-5 can improve both heart and muscle problems in Barth syndrome. Testing the drug on cells from Barth syndrome patients and in fruit fly models of the disease, the drug boosted cellular energy production by up to 50%.

Some chemotherapy agents cause mutations and premature ageing in healthy blood, new research shows.