Latest Articles

This article explores how synthetic biology is revolutionizing therapeutics through engineered cells, precision genetic circuits and AI-driven design, with applications in cancer treatment, vaccine development and next-generation immunotherapies.

Today, our approach to irAE management is predominantly reactive. Clinical guidelines, while increasingly robust, are designed to detect and treat toxicity after it arises. This framework, though necessary, falls short of what is now possible.

The tumor microenvironment is a harsh environment where metabolic adaptations are key. In this article, we explore how the metabolic constraints of the TME influence cancer and immune cells and dive into the metabolic cross-talk between them.

Traditionally, viruses have been thought of as a burden that cause disease. Now, viruses are being harnessed to tackle diseases that medicines can’t, helping fight cancer, genetic disorders and even infectious diseases.

Learn how population genomics has evolved, its role in health and disease and the challenges ahead.

Drug discovery efforts have expanded beyond the traditional approaches of small molecules and antibodies to include cells. This article explores the use of microfluidic methods for high-throughput screening of cell-based drug products.

Researchers discuss how organoids and organ-on-a-chip technologies are transforming women’s health research. By mimicking female-specific tissues, these models uncover new insights into diseases that affect women, such as breast cancer.

A recent randomized control trial posits arginine depletion as a viable alternative to current systemic treatments based on chemotherapy and immunotherapy for mesothelioma.

The complexity of the TME in vivo limits the conclusions that can be drawn from in vivo models. Optimizing cell culture models to mimic the TME is vital to understanding cancer progression and the development of optimized therapies.

Endometrial organoids, 3D cell cultures mimicking the endometrium, offer new opportunities in endometriosis research. These models are key in studying drug targets, fertility issues and gynecological cancers.