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3D illustration of molecular structure emerging from capsules, symbolizing antidepressant drugs.
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Estonian Study Links Antidepressant Side Effects to Genetics

Researchers at the University of Tartu found that genetic differences in the CYP2C19 gene significantly affect how people tolerate antidepressants. Slow metabolizers faced 49% higher side effect risk, while ultra-rapid ones had reduced risk.
3D illustration of immune cells attacking a cancer cell, representing cancer immunotherapy.
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Repurposed Drug May Reduce Cancer Immunotherapy Side Effect

A team of researchers has identified a potential new strategy to prevent, or even reverse, immune checkpoint inhibitor–induced type 1 diabetes.
Fork holding a curled measuring tape against a yellow background symbolizing weight loss.
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Cysteine Depletion Triggers Fat Burning and Weight Loss

A study reveals that reducing the amino acid cysteine triggers fat browning and weight loss. Researchers found calorie restriction lowers cysteine in human fat tissue, while animal models showed dramatic fat loss when cysteine was depleted.
Drug capsules spilling across a table.
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Eliminating Lifelong Immunosuppressive Medications for Transplant Patients

Mayo Clinic researchers examined whether people who simultaneously received both a kidney and stem cell transplant from a closely matched sibling could discontinue all immunosuppressive medications after a year.
A white model of a human brain, with multicoloured wires stretching out from either side of it.
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Common Cough Medicine Could Slow Parkinson’s-Related Dementia

Ambroxol – a common cough medicine in Europe – may prevent the progression of dementia in patients with Parkinson's disease, a new trial suggests.
The outline of a liver, filled with interconnected dots illustrating vasculature and the connection between cells.
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Scientists Improve Liver Organoids for Research Into Hemophilia

Researchers have created liver tissue that grows its own blood vessels, improving research into hemophilia and liver damage.
Rod-shaped drug resistant tuberculosis bacteria.
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Critical Genes in "Zombie" Tuberculosis Pathogens Identified

New research identifies key genes in "zombie" TB cells resistant to antibiotics, bringing new drugs one step closer.
A female surgeon in a surgery room, surrounded by her surgical team.
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Physician Develops Drug That Makes Nerve Tissue Glow, Enabling Safer Surgery

A surgeon has helped develop and test a first-of-its-kind drug that binds to nerve tissue and fluoresces – emits light – enabling surgeons to better see the nerves they’re trying to work around.
A bowl of different drugs next to various herbs, representing natural compounds in drug discovery.
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Combined Therapy Overcomes Drug Resistance in Autoimmune Diseases

A study found that combining the active ingredient extracted from the traditional Chinese medicine Astragalus membranaceus with the widely used Western drug methotrexate can effectively reduce chronic inflammation in autoimmune diseases.
A white mouse on top of some test tubes, used in animal models for drug testing.
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Mouse Model for Ultra-Rare Neurological Disorder Could Pave the Way for Gene Editing Therapies

Scientists have developed mouse models that survive premature death and enable preclinical testing of alternating hemiplegia of childhood, or AHC, a devastating and sometimes fatal neurological disorder that affects about one in a million children.
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