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Global Childhood Vaccination Uptake Stalls
Since 2010, progress in vaccine coverage has stalled or reversed in many countries, with measles vaccination declining in 100 of 204 countries between 2010 and 2019.

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DNA Repair Protein Offers Therapeutic Target for Age-Related Diseases
New research identified a protein called protein disulfide isomerase that helps repair serious DNA damage, providing a target to prevent and treat aging.

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Parental Genes Decide a Honey Bee’s Fate
Researchers discovered that genetic conflict between paternal and maternal genes determines whether honey bee larvae become queens or workers. The study reveals how histone modifications control gene expression and how this shapes honey bee behavior.

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Vaccine Protects Against Yeast Infections in Mouse Model
A vaccine developed by University of Georgia researchers successfully protects against and treats vaginal yeast infections in mice, according to a newly published study.

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Dual-Adjuvant HIV Vaccine Offers Strong Protection With One Dose
Researchers have shown that they can generate a strong immune response to HIV with just one vaccine dose, by adding two powerful adjuvants – materials that help stimulate the immune system.

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CRISPR Brings Genes Closer Together in New Approach to Gene Therapy
Researchers have found a promising new method for gene therapy. They successfully restarted inactive genes by bringing them closer to genetic switches on the DNA called enhancers.

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Personalized Cancer Vaccines Slow Tumor Recurrence in Mice
Using a newly discovered byproduct of dying cancer cells, University of Wisconsin–Madison researchers are developing personalized vaccines that could help keep aggressive tumors from recurring.

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Enabling the Body To Engineer Its Own CAR T Cells
A new approach induces the patient’s body to produce its own CAR-T cells, relying on the same messenger RNA (mRNA) technology that was instrumental for some COVID-19 vaccines.

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First Use of CAR T-Cell Therapy for Autoimmune Neuropathy
A team of physicians from Bochum are the first to successfully use CAR T-cell therapy to treat two patients with a rare autoimmune disease of the peripheral nervous system.

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AI Approach Could Make Designing Proteins for New Medicines Easier
Scientists have created an AI approach that could make designing proteins for new medicines easier. This new AI approach outperforms current methods for "inverse protein folding" – a critical part of the process of creating new proteins.
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