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Transplanting healthy human glial progenitor cells into the brains of adult animal Huntington's disease models not only slowed motor and cognitive decline but also extended lifespan.

Pembrolizumab, an immune checkpoint inhibitor, has been approved by the US Food and Drug Administration for the treatment of patients with resectable locally advanced head and neck squamous cell carcinoma whose tumors express PD-L1.

Researchers successfully developed a platform that utilizes microbubbles to deliver gene-targeted nanoparticles capable of breaking down biofilms, offering an innovative solution for treating infections resistant to conventional antibiotics.

In modern immunotherapy, modified immune cells are introduced into the body to attack tumors and other targets. Researchers have now developed a method for tracking these cells in the body.

In a 13-year follow-up by St. Jude Children’s Research Hospital and University College London published in The New England Journal of Medicine, researchers demonstrate the long-term viability of gene therapy for the treatment of hemophilia B.

Inspired by cancer immunotherapy, scientists engineered immune cells equipped with specialized targeting devices called chimeric antigen receptors (CARs) that can distinguish and respond to tau tangles and various forms of toxic amyloid plaques.

A new method, based on the use of molecules known as polypurine hairpins, facilitates the uptake of cholesterol by cells and prevents it from accumulating in the arteries without causing the side effects of the most common statin-based drugs.

Combining elements of four hormones into a single drug, researchers hope a next-generation weight loss drug will address not only obesity, but associated conditions like type 2 diabetes, cancer, and cardiovascular disease.

A new sorting system has been developed to quickly and efficiently separate gastruloids, offering a significant step forward in research on early human development.

Researchers have developed new CAR-T cells to target malignant tumors. Their method targeted a protein found in high amounts on many types of cancer cells (Eva1) and successfully eliminated tumors in lab mice.