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Neurons form connections between themselves.
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Dystroglycan Plays a Key Role in Connections Between Nerve Cells

New research reveals that the protein Dystroglycan plays a critical role in forming and maintaining connections between nerve cells in the cerebellum.
A plastic model of human lungs, bisected to reveal blood vessels and air sacs.
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Mini-Lungs Closely Mirror Human Lung Development

Researchers have successfully grown miniature lungs from stem cells – complete with their own functioning blood vessel networks.
Intertwined neurons, illustrating cell death prevention in Parkinson's.
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Enzyme Inhibition Halts Cell Death in Parkinson's Disease

Putting the brakes on an enzyme might rescue neurons that are dying in Parkinson's disease, stabilizing the progression of symptoms.
Illustration of a cross-section of mitochondrial organelle.
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Aggressive Skin Cancer Driven by Mitochondrial Processes

A new study led by researchers at Lund University in Sweden reveals that melanoma can, in some cases, be driven by mitochondrial processes, which can be effectively targeted using existing drugs.
A photograph of stained cancer tissues under a microscope.
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Bioengineered Tumor Model Aids Fight Against Abdominal Cancer

Researchers have developed a bioengineered hydrogel platform capable of preserving patient-derived tumor tissues for longer periods, a breakthrough that could enhance drug testing for abdominal cancer.
A close-up of a section of the 3D structure of a protein.
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Age and Disease-Related Inflammation Linked to Protein Released by Cells

Researchers identified a protein that could be targeted to block chronic inflammation. Crucially, this strategy would not interfere with acute inflammation, allowing the immune system to continue responding appropriately to short-term threats.
A malaria pathogen attacks a red blood cell.
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Proteins in a Parasite-Specific Organelle Could Form Antimalarial Targets

Researchers have identified two proteins in an organelle specific to Plasmodium falciparum that could be used as drug targets for novel antimalarials.
A female scientist in gloves and a mask holding up a red pill, representing drug discovery.
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Mitochondria-Homing Drug Shows Promise for Barth Syndrome

An oral drug called MA-5 can improve both heart and muscle problems in Barth syndrome. Testing the drug on cells from Barth syndrome patients and in fruit fly models of the disease, the drug boosted cellular energy production by up to 50%.
Bacteria with long flagella, a potential target to slow antibacterial resistance.
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Researchers Target the Flagellum in the Fight Against Antibiotic Resistance

Targeting the flagellum to deliver a critical, but not fatal, blow to bacteria could help in the fight against antibiotic resistance.
A female surgeon in a blue surgical robe and face mask.
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A Safer, Eco-Friendly Polymer for Implantable Medical Devices

Scientists have developed a new polymer, PHOx, which could significantly improve the safety of implantable medical devices while also being more environmentally friendly.
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