Latest App Notes & Case Studies

App Note / Case Study
Rapidly Detect Mycoplasma Contamination
This info kit highlights a rapid detection kit for the sensitive and reliable detection of mycoplasma in biological products.

App Note / Case Study
Studying the Link Between Cell Migration and Neurodegenerative Disease With iPSC-derived Microglia
In this application note, researchers from Medicines Discovery Catapult (MDC) evaluated the suitability of iPSC-derived microglia as a model for studying the mechanics of microglia activation, shedding light on their role in neurodegeneration and the potential for therapeutic targets.

App Note / Case Study
Improving Physiological Relevance in Neurological Disease Drug Development
This case study explores the use of human iPSC-derived microglial cells as a more reliable model for neurobiological drug development.

App Note / Case Study
A High-Throughput Platform for Fluorescence Image-Based Neurite Outgrowth Analysis
This application note introduces an automated solution for flexible and sensitive multichannel analysis of neurite outgrowth for high-throughput assays.

App Note / Case Study
Preventing Cell Death
The cell wall components of gram-negative bacteria are designated as endotoxins. They have a hydrophilic polysaccharide and a lipophilic lipid component and are highly heat and pH stable.

App Note / Case Study
Assessing the Functionality of PBMCs After Cryopreservation
As PBMCs continue to see an increase in use in the testing of new biological therapeutic compounds, ensuring purified cells retain functionality after cryopreservation is critical.

App Note / Case Study
High-Resolution mRNA Poly(A) Tail Analysis With CGE-UV
This application note describes how capillary gel electrophoresis with UV detection (CGE-UV) can attain single-nucleotide resolution over a broad size range, making it suitable for the development of QC assays.

App Note / Case Study
Large-Scale Expansion of PSCs To Support Cell Therapy Manufacturing
This application note introduces a suspension medium for use in the production of pluripotent stem cells (PSCs) for allogeneic therapies, enabling a seamless transition from research to clinical settings.

App Note / Case Study
Automate Assembly Cloning Using a Liquid Handling Platform
This application note presents a case study where a manual cloning approach was adapted with an automated platform to expedite experiments on 96-well and 384-well plates.

App Note / Case Study
Single-Use Technology Designed for Small Batches in Gene Therapy Manufacturing
But how do you purify small volumes for preclinical and clinical studies without losing too much to processing or leaving capacity unused?
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