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Flu Vaccine Adjuvant Improves Cross Protection Against Influenza Viruses
Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus challenges when combined with a mucosal adjuvant, according to a study.

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Scientists Target Brain Cancer With Innovative Myosin Motor Drug
A potential treatment for glioblastoma crafted by scientists at The Wertheim UF Scripps Institute renders the deadly brain cancer newly sensitive to both radiation and chemotherapy drugs, and blocks the cancer’s ability to invade other tissues.

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No Evidence That Ibuprofen and Certain Blood Pressure Drugs Trigger Microscopic Colitis
There is a perception that common drugs such as ibuprofen and SSRI preparations can trigger the intestinal disease microscopic colitis. However, a new study from Karolinska Institutet and Harvard Medical School suggests that this is not the case.

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Motion Capture Improves Mouse Modeling of Motor Disorders
Researchers have introduced a mouse motion capture method that provides very high-resolution measurement of mouse movement. Their marker-based approach avoids the need for extensive data processing with AI or machine learning.

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Repurposed Parkinson’s Drug Treats Persistent Depression
In a large clinical trial, pramipexole was found to be substantially more effective than a placebo at reducing the symptoms of treatment resistant depression over the course of nearly a year.

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Your Genes Determine if Anxiety Medication Will Be Effective
Nearly half of all patients with anxiety or depression experience no effect from the drugs they are first prescribed. Research shows that our genes may predict which drugs work, potentially allowing doctors to choose the right drug on the first try.

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Slowing Down the Intracellular Transport of RNA-Based Drugs Improves Efficacy
A recent study reveals that slowing down the intracellular transport of RNA-based drugs can significantly enhance their effectiveness. These therapeutics are currently used to treat rare genetic diseases.

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Machine Learning Algorithm Predicts Protein-Water Contributions to Drug Binding
Water molecules represent a powerful but largely underappreciated foothold in drug binding studies. See how ColdBrew can provide accurate water displacement predictions for protein structures, providing a clearer landscape for drug discovery.

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Gene Therapy Normalizes Blood Flow in the Brain
Findings from three patients in a gene therapy clinical trial showed that gene therapy treatment significantly improved blood flow in the brain. These results demonstrate that people with associated risk factors should be considered for trials.

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Novel Brain Imaging Approach Reveals How a Parkinson’s Drug Affects the Brain
Researchers have used magnetoencephalography brain imaging technology to determine how the drug levodopa, the main drug used in dopamine replacement therapy, affects signals in the brain.
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