Detection of Endogenous Biomarkers in Complex Matrices
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Quantifying endogenous biomarkers such as corticosteroids and endocannabinoids is critical for advancing diverse research fields, from stress-related disease to forensic science.
Yet, analysing biological matrices like hair and nails presents significant obstacles due to their keratinized nature and ultra-low analyte concentrations.
This webinar presents a highly sensitive LC-MS/MS workflow that overcomes the limitations of traditional methods and allows for the detection of biomarkers in keratinized matrices.
Watch the webinar to discover:
- A workflow for biomarker detection in keratinized matrices at femtogram levels
- Sample preparation strategies that maximize recovery and minimize background
- Calibration and quantification approaches tailored for endogenous compound analysis
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