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An uninjured (left) and injured adult zebrafish heart with neural crest cells labeled magenta. Note the neural crest cells activated around the edge of the injury in preparation for regenerating the heart muscle.
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CRISPR May Help Humans Regrow Heart Tissue, Inspired by Fish

UC Berkeley and Caltech researchers identified a gene circuit in zebrafish that allows heart regeneration after injury. Using CRISPR, they pinpointed key genes like egr1 that may reactivate heart repair in humans.
A group of stem cells used in stem cell therapy.
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Adult Stem Cells Isolated From a Non-Human Primate for the First Time

For the first time, researchers have discovered and isolated adult stem cells from a non-human primate. This finding could transform the foundation for how we develop stem cell treatments.
CGRP-expressing neurons (green) in the parvocellular subparafascicular nucleus (SPFp) of the thalamus.
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Pain's Emotional Edge Traced to New Brain Pathway

Salk Institute scientists identified a brain circuit that gives pain its emotional intensity. This CGRP-linked spinothalamic pathway connects to the amygdala, triggering distress and avoidance.
Various drugs such as antibiotics on a desk with one pill under a magnifying glass, representing drug repurposing.
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Antibiotics Show Promise as Alternative to Toxic Tuberculosis Drug

Clinical trials have shown the safety and efficacy of two promising antibiotics as potential alternatives to linezolid in the treatment of tuberculosis.
Close-up of a bat hanging upside down from a leaf, wings partially wrapped around its body.
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Bat Brain Activity Sheds Light on Human Memory

Researchers recorded hundreds of neurons in freely flying bats, uncovering how neural replay and theta sequences support memory and planning. The study revealed that replay duration is fixed regardless of flight length.
A tap runs water.
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Reducing Tap Water Contaminants Like Arsenic May Prevent Over 50,000 Cancer Cases

Drinking water treatment that pursues a multi-contaminant approach, tackling several pollutants at once, could prevent more than 50,000 lifetime cancer cases in the US, finds a new peer-reviewed study by the Environmental Working Group.
A reflection of a marsh in British Columbia, Canada. Conifer tree line visible.
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Some Crabs and Clams in British Columbia Have Evaded Commercialization for 3,000 Years

Combining paleontological tools and archaeological data with conservation research, the paper finds that, for the past 3,000 years, crab and clam species have remained stable in the Broken Group Islands off the west coast of Vancouver Island.
Illustration of a cell's ultrastructure, including the organelles that make up a cell.
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Unknown Organelle Discovered Inside Our Cells

The organelle, a type of specialized structure, has been dubbed a “hemifusome” by its discoverers at the University of Virginia School of Medicine and the National Institutes of Health.
Woman wearing orange hoodie running.
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Gut Microbes Key in Exercise's Cancer-Fighting Effect

A new study, for the first time, shows how exercise improves cancer outcomes and enhances response to immunotherapy in mice by reshaping the gut microbiome.
Cacti with wide round leaves, red bulbous fruit visible. Clear blue sky.
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The Duration of Heat Waves is Accelerating Faster Than Global Warming

New research finds that not only will climate change make heat waves hotter and longer, but the lengthening of heat waves will accelerate with each additional fraction of a degree of warming.
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