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Illustration of cancerous cells infiltrating a healthy cellular environment.
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Decoding the Evolution of Cancer Cells

Researchers at the German Cancer Research Center (DKFZ) have now developed a method that allows for the first time to reconstruct the temporal development—the evolution—of cancerous cells from a single tissue sample.
Galapagos tortoise.
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Only 1% of Turtles Get Cancer

A new study from researchers at the University of Nottingham provides the strongest evidence to date that cancer is extremely rare in turtles.
Microscopic view of bone marrow cells, relevant to liquid biopsy analysis in cancer diagnostics.
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RNA-Based Liquid Biopsy Detects Early Colon Cancer With 95% Accuracy

A study from the University of Chicago introduces an RNA-based liquid biopsy that detects early-stage colorectal cancer with 95% accuracy. The test overcomes the limitations of DNA-based methods.
3D illustration of immune cells attacking a cancer cell, representing cancer immunotherapy.
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Repurposed Drug May Reduce Cancer Immunotherapy Side Effect

A team of researchers has identified a potential new strategy to prevent, or even reverse, immune checkpoint inhibitor–induced type 1 diabetes.
The image, captured with a high-powered microscope over 9-minute intervals, is color-coded from early to late time points showing wave activity (green, blue, purple, pink, red).
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Why Aggressive Cancers Pulse With Rhythmic Energy

In a bid to better understand how cancer cells power their explosive growth and spread, scientists say they have shed new light on the location and function of power-generating waves on the cell membrane.
Illustration of 3D microscopic cancer cells.
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Why Some Prostate Tumors Are Resistant to Treatment

While many patients experience long-term benefits from cancer treatment, some will derive no benefit whatsoever. The study examined RNA sequencing data and clinical outcomes from several prostate cancer clinical trial datasets.
A linear accelerator (LINAC) is set up to deliver stereotactic radiosurgery.
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AI Support Improves Accuracy in Breast Cancer Screening

AI-assisted mammogram reading helps radiologists focus on suspicious areas, increasing lesion detection without lengthening reading time.
Women having her eyes tested.
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CRISPR Screens Reveal Genetic Weak Spot in Metastatic Eye Cancer

Researchers used CRISPR to find a pair of genes that show strong potential as a new therapeutic target for uveal melanoma – a rare eye cancer.
Loss of MCL-1 triggers severe mitochondrial damage (shown in the right panel). Mitochondria are shown in red, cell nuclei in blue.
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MCL-1 Discovery Unlocks New Cancer Strategies

Landmark research on MCL-1, a critical protein that is an attractive target for cancer drug development, helps explain why some promising cancer treatments are causing serious side effects.
X-ray image of patient with lung cancer.
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Corticosteroids Shown To Weaken Effectiveness of Immunotherapy

A new study showed that high doses of steroids, when given before and/or during a specific type of immunotherapy, caused patients’ tumors to shrink less than those of patients not on steroids. Those patients also did not live as long.
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