PAL System Micro-SPE Cartridges — A Green Solution

μSPE offers significant advancements in automated sample preparation by eliminating analyte dilution and the need for solvent evaporation or cartridge drying. This streamlined approach is particularly well-suited for applications such as QuEChERS pesticide analysis, veterinary drug testing, filtration of life science samples and more. By replacing traditional manual SPE workflows that require large solvent volumes, μSPE represents a step forward in green analytical chemistry by reducing waste and lowering costs. The μSPE cartridge functions like a compact liquid chromatography (LC) column, utilizing only micro-volumes of sample and elution solvents. With a syringe serving as the solvent pump, consistent flow and pressure ensure high repeatability in automated procedures, enhancing efficiency and reliability in the laboratory. By automating repetitive tasks and minimizing manual intervention, μSPE accelerates throughput without compromising accuracy. μSPE streamlines the sample preparation process, significantly reducing labour time and solvent usage, allowing scientists to spend more time on valuable data analysis. The adaptable nature of μSPE Cartridge design and their inherent compatibility with automation platforms offer significant value for high-throughput analytical laboratories. Depending on the selection of sorbent chemistry and the configuration of the extraction protocol, μSPE can be implemented to selectively retain either matrix components or the target analytes themselves. The targeted removal of complex matrix constituents can streamline subsequent chromatographic analysis, improving analyte signal clarity and facilitating lower limits of detection. This capability is particularly advantageous when investigating contaminants such as PFAS or pesticides, which frequently occur at trace concentrations within complex environmental or biological matrices.